Symbol
Name
ID

Cdc42
cell division cycle 42
MGI:106211

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Mouse Phenotypes

intracranial hemorrhage

intraventricular hemorrhage

absent brain ependyma motile cilia

abnormal neuronal precursor proliferation

abnormal embryonic neuroepithelium morphology

abnormal telencephalon development

abnormal cortical plate morphology

abnormal cortical ventricular zone morphology

abnormal folding of telencephalic vesicles

small embryonic telencephalon

holoprosencephaly

hydrocephaly

cerebral aqueductal stenosis

abnormal brain ventricle morphology

abnormal brain ependyma morphology

enlarged brain ventricles

enlarged lateral ventricles

enlarged third ventricle

abnormal lateral ventricle morphology

abnormal third ventricle morphology

abnormal cerebral aqueduct morphology

abnormal cerebral cortex morphology

abnormal neocortex morphology

thin cerebral cortex

small olfactory bulb

abnormal glial cell morphology

abnormal myelin sheath morphology

decreased neuronal precursor cell number

abnormal spinal cord central canal morphology

Availability

Mouse Genotype

Cdc42^tm1.1Ayam/Cdc42^tm1.1Ayam
Tg(Mpz-cre)94Imeg/0 (conditional)

Cdc42^tm1.1Rac/Cdc42^tm1.1Rac
Tg(GFAP-cre)25Mes/0 (conditional)

Cdc42^tm1.1Rac/Cdc42^tm1.1Rac
Tg(Nes-cre)1Kln/0 (conditional)

Cdc42^tm1Brak/Cdc42^tm1Brak
Tg(Plp1-cre/ERT2)1Ueli/0 (conditional)

Cdc42^tm1Yizh/Cdc42^tm1Yizh
Foxg1^tm1(cre)Skm/Foxg1⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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